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Dapiprazole Hydrochloride
CAS No. 72822-13-0
Dapiprazole Hydrochloride ( —— )
产品货号. M19044 CAS No. 72822-13-0
达哌唑盐酸盐是一种 α-1-肾上腺素能拮抗剂，通过阻断血管（动脉、小动脉和静脉）、胃肠道和虹膜放射状平滑肌的平滑肌中的 α-肾上腺素能受体发挥作用。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 10MG | ￥348 | 有现货 |
|
| 25MG | ￥721 | 有现货 |
|
| 50MG | ￥1110 | 有现货 |
|
| 100MG | ￥1596 | 有现货 |
|
| 200MG | ￥2406 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
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产品名称Dapiprazole Hydrochloride
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注意事项本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
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产品简述达哌唑盐酸盐是一种 α-1-肾上腺素能拮抗剂，通过阻断血管（动脉、小动脉和静脉）、胃肠道和虹膜放射状平滑肌的平滑肌中的 α-肾上腺素能受体发挥作用。
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产品描述Dapiprazole Hydrochloride is an alpha-1-adrenergic antagonist that acts by blocking alpha-adrenergic receptors in the smooth muscle of blood vessels (arteries, arterioles and veins), gastrointestinal tract, and radial smooth muscle of the iris.(In Vivo):Dapiprazole hydrochloride (0-10 mg/kg or 0-3 mg/mice; i.p. or i.c.v.; once) reduces the overall severity of the opiate withdrawal symptoms in mice.
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体外实验——
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体内实验Dapiprazole hydrochloride (0-10 mg/kg or 0-3 mg/mice; i.p. or i.c.v.; once) reduces the overall severity of the opiate withdrawal symptoms in mice. Animal Model:Swiss Albino male CD-1 mice weighing 20 -25 g, acute dependence model Dosage:5, 7.5 and 10 mg/kg (i.p.) or 0.5, 1 and 3 mg/mice (i.c.v.), once Administration:Intraperitoneal injection or intracerebroventricular administration, once Result:Decreased jumping behavior, head shakes and paw shakes when administered just before naloxone.
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同义词——
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通路Others
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靶点Other Targets
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受体α1-adrenergic receptor
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研究领域Others-Field
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适应症——
化学信息
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CAS Number72822-13-0
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分子量361.92
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分子式C19H28ClN5
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纯度>98% (HPLC)
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溶解度DMSO : ≥ 31 mg/mL; 85.66 mM
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SMILESCc1ccccc1N1CCN(CC1)CCc1nnc2n1CCCC2.Cl
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Hogan TS., et al. Dose-response study of dapiprazole HCl in the reversal of mydriasis induced by 2.5% phenylephrine. J Ocul Pharmacol Ther. 1997 Aug;13(4):297-302.
产品手册
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